Understanding Bacteriophage Tail Fiber
In this review, we comprehensively summarize how the tail fibers of the T4 phage recognize host surface receptors at single-molecule and atomic levels.
Get QuoteBecause of the large size and simple linear structure of the assembled tail fiber, crystallizing whole tail fibers has proved challenging, although some fragments of tail fiber proteins have been asse...
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In this review, we comprehensively summarize how the tail fibers of the T4 phage recognize host surface receptors at single-molecule and atomic levels.
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The precise arrangement of amino acids in the receptor-binding domain of the tail fiber determines which bacterial surface molecules it can recognize, thereby defining the phage''s ability to
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The tail completion protein, product of another highly conserved gene, is believed to be present at the proximal end of the siphotail, possibly to help correct positioning of the DNA after
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Here, we provide the first molecular description of a tail fiber tip. Extensive mutational, structural, and biochemical analyses show that the ball-shaped tip contains patches of binding sites
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This innovative paper describes how the host range of R-type pyocins can be reprogrammed by replacing parts of the tail fibres between phages with different host ranges.
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The rate of tail fiber attachment as measured by activation of the particles to infectious phage is strongly dependent upon the presence of whisker antigen in the extract.
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Because of the large size and simple linear structure of the assembled tail fiber, crystallizing whole tail fibers has proved challenging, although some fragments of tail fiber proteins have been assembled,
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To address this challenge, an overwhelming number of phages use a structure known as a tail. The tail creates a conduit between the phage capsid and host cytoplasm and allows the phage particle to
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At the far end of the tail are one or more receptor binding proteins (the tail fibers), also described as adhesins.
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Caudovirales (tailed bacterial viruses) usually have fibers attached to the distal end of their tail. The preassembled are attached to the tail. The pathway of fibers assembly has been well studied in
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